{"id":40643,"date":"2014-02-17T09:48:24","date_gmt":"2014-02-17T04:18:24","guid":{"rendered":"https:\/\/new.editage.cn\/insights\/research\/muscle-recovery-possible-in-elderly-mice"},"modified":"2026-01-08T11:16:02","modified_gmt":"2026-01-08T05:46:02","slug":"muscle-recovery-possible-in-elderly-mice-5008","status":"publish","type":"research","link":"https:\/\/www.editage.cn\/insights\/muscle-recovery-possible-in-elderly-mice-5008\/","title":{"rendered":"Muscle recovery possible in elderly mice"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size:14px;\"><span style=\"font-family:verdana,geneva,sans-serif;\">Over time, stem cells in damage-repairing muscle tissues struggle to regenerate. In a new study, scientists have identified a process by which the older muscle stem cell populations can be rejuvenated to function like younger cells. Using 2-year-old mice, they found that many muscle stem cells isolated exhibited elevated levels of activity in a biological cascade called the p38 MAP kinase pathway. The scientists were able to identify a defect inherent to old muscle stem cells and a way to overcome the defect. This finding may have implications in the area of therapeutic care for the elderly. Read more in <em><a href=\"https:\/\/www.nature.com\/nm\/journal\/vaop\/ncurrent\/full\/nm.3465.html\" rel=\"nofollow\" target=\"_blank\">Nature Medicine<\/a><\/em>.<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size:14px;\"><span style=\"font-family:verdana,geneva,sans-serif;\">JD Bernet et al. <em>Nature Medicine<\/em>, 2014. DOI: 10.1038\/nm.3465<\/span><\/span><\/p>\n","protected":false},"author":27,"featured_media":60567,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"new_tags":[356],"series":[],"subject":[365,2444],"class_list":["post-40643","research","type-research","status-publish","has-post-thumbnail","hentry","new_tags-356","subject-365","subject-sheng-wu-hua-xue-yi-chuan-xue-yu-fen-zi-sheng-wu-xue-314"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Muscle recovery possible in elderly mice | Editage Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.editage.cn\/insights\/muscle-recovery-possible-in-elderly-mice-5008\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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