{"id":40623,"date":"2014-10-30T07:19:15","date_gmt":"2014-10-30T01:49:15","guid":{"rendered":"https:\/\/new.editage.cn\/insights\/research\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs"},"modified":"2026-01-08T11:16:14","modified_gmt":"2026-01-08T05:46:14","slug":"tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988","status":"publish","type":"research","link":"https:\/\/www.editage.cn\/insights\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988\/","title":{"rendered":"Tiny stomachs grown in lab to study diseases and test drugs"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-family:verdana,geneva,sans-serif;\"><span style=\"font-size:14px;\">Scientists at Cincinnati Children&#8217;s Hospital Medical Center in Ohio were successful in creating small stomachs, also called &#8216;gastric organoids,&#8217; from stem cells. The researchers persuaded pluripotent stem cells to grow specifically into stomachs using a cocktail of proteins that created a pathway of interactions that lead to organ formation. The resulting organoids were found to be strikingly similar to an actual human stomach in their gland structure but lacked blood cells, immune cells, or the ability to process food. Researchers tested the tiny stomachs by injecting them with <em>Helicobacter pylori<\/em>, a bacterium that can cause ulcers and stomach cancer in humans. The effects of the bacterium on the lab-grown stomachs mirrored the effects it creates in human stomachs. The researchers now plan to use these artificially grown stomachs to study diseases such as cancer, and to test the stomach&#8217;s response to drugs.<\/span><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-family:verdana,geneva,sans-serif;\"><span style=\"font-size:14px;\">Read more in <em><a href=\"https:\/\/www.nature.com\/news\/tiny-human-stomachs-grown-in-the-lab-1.16229\" rel=\"nofollow\" target=\"_blank\">Nature<\/a><\/em>.<\/span><\/span><\/p>\n","protected":false},"author":27,"featured_media":60567,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"new_tags":[356],"series":[],"subject":[365,2444],"class_list":["post-40623","research","type-research","status-publish","has-post-thumbnail","hentry","new_tags-356","subject-365","subject-sheng-wu-hua-xue-yi-chuan-xue-yu-fen-zi-sheng-wu-xue-314"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tiny stomachs grown in lab to study diseases and test drugs | Editage Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tiny stomachs grown in lab to study diseases and test drugs | Editage Insights\" \/>\n<meta property=\"og:description\" content=\"Scientists at Cincinnati Children&#8217;s Hospital Medi [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988\" \/>\n<meta property=\"og:site_name\" content=\"Editage Insights\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Editage\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-08T05:46:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png\" \/>\n\t<meta property=\"og:image:width\" content=\"656\" \/>\n\t<meta property=\"og:image:height\" content=\"336\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Editage\" \/>\n<meta name=\"twitter:label1\" content=\"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 \u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988\\\/\",\"url\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988\",\"name\":\"Tiny stomachs grown in lab to study diseases and test drugs | Editage Insights\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#primaryimage\"},\"image\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"datePublished\":\"2014-10-30T01:49:15+00:00\",\"dateModified\":\"2026-01-08T05:46:14+00:00\",\"breadcrumb\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#breadcrumb\"},\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\\\/\\\/localhost\\\/editagechinanew\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#primaryimage\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"contentUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"width\":656,\"height\":336},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Tiny stomachs grown in lab to study diseases and test drugs\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#website\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\",\"name\":\"Editage Insights\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#organization\",\"name\":\"Editage Insights\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Editage Insights\"},\"image\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/Editage\",\"https:\\\/\\\/x.com\\\/Editage\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Tiny stomachs grown in lab to study diseases and test drugs | Editage Insights","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988","og_locale":"zh_CN","og_type":"article","og_title":"Tiny stomachs grown in lab to study diseases and test drugs | Editage Insights","og_description":"Scientists at Cincinnati Children&#8217;s Hospital Medi [&hellip;]","og_url":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988","og_site_name":"Editage Insights","article_publisher":"https:\/\/www.facebook.com\/Editage","article_modified_time":"2026-01-08T05:46:14+00:00","og_image":[{"width":656,"height":336,"url":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@Editage","twitter_misc":{"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4":"1 \u5206"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.editage.cn\/insights\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988\/","url":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988","name":"Tiny stomachs grown in lab to study diseases and test drugs | Editage Insights","isPartOf":{"@id":"https:\/\/www.editage.cn\/insights\/#website"},"primaryImageOfPage":{"@id":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#primaryimage"},"image":{"@id":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#primaryimage"},"thumbnailUrl":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","datePublished":"2014-10-30T01:49:15+00:00","dateModified":"2026-01-08T05:46:14+00:00","breadcrumb":{"@id":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#breadcrumb"},"inLanguage":"zh-Hans","potentialAction":[{"@type":"ReadAction","target":["http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988"]}]},{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#primaryimage","url":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","contentUrl":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","width":656,"height":336},{"@type":"BreadcrumbList","@id":"http:\/\/localhost\/editagechinanew\/tiny-stomachs-grown-in-lab-to-study-diseases-and-test-drugs-4988#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.editage.cn\/insights\/"},{"@type":"ListItem","position":2,"name":"Tiny stomachs grown in lab to study diseases and test drugs"}]},{"@type":"WebSite","@id":"https:\/\/www.editage.cn\/insights\/#website","url":"https:\/\/www.editage.cn\/insights\/","name":"Editage Insights","description":"","publisher":{"@id":"https:\/\/www.editage.cn\/insights\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.editage.cn\/insights\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-Hans"},{"@type":"Organization","@id":"https:\/\/www.editage.cn\/insights\/#organization","name":"Editage Insights","url":"https:\/\/www.editage.cn\/insights\/","logo":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Editage Insights"},"image":{"@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/Editage","https:\/\/x.com\/Editage"]}]}},"_links":{"self":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research\/40623","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research"}],"about":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/types\/research"}],"author":[{"embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/users\/27"}],"version-history":[{"count":1,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research\/40623\/revisions"}],"predecessor-version":[{"id":60250,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research\/40623\/revisions\/60250"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/media\/60567"}],"wp:attachment":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/media?parent=40623"}],"wp:term":[{"taxonomy":"new_tags","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/new_tags?post=40623"},{"taxonomy":"series","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/series?post=40623"},{"taxonomy":"subject","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/subject?post=40623"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}