{"id":40601,"date":"2015-07-07T07:00:28","date_gmt":"2015-07-07T01:30:28","guid":{"rendered":"https:\/\/new.editage.cn\/insights\/research\/researchers-unravel-a-3-d-map-of-capsid-protein"},"modified":"2026-01-08T11:16:09","modified_gmt":"2026-01-08T05:46:09","slug":"researchers-unravel-a-3d-map-of-capsid-protein-4966","status":"publish","type":"research","link":"https:\/\/www.editage.cn\/insights\/researchers-unravel-a-3d-map-of-capsid-protein-4966\/","title":{"rendered":"Researchers unravel a 3-D map of capsid protein"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size:14px;\">Researchers at the University of Missouri have been able to procure detailed images of the capsid protein, which is a key protein in HIV, in its natural state. Stefan Sarafianos \u2013 an associate professor of molecular microbiology and immunology and the Chancellor&#8217;s Chair of Excellence in molecular virology in the University of Missouri School of Medicine \u2013 who is heading the team of researchers, explains, \u201cThe capsid shell acts as an &#8216;invisibility cloak&#8217; that hides the virus&#8217; genetic information, the genome, while it is being copied in a hostile environment for the virus.\u201d Using a technique called X-ray crystallography, Sarafianos and his team created the most complete model yet of an HIV capsid protein and developed the protein\u2019s 3-D map. The model revealed that the protein consists of water molecules, which help the capsid shell to be flexible and assume different forms, a critical requirement for the life cycle of the HIV virus. This model of the capsid protein will help in the development of antiviral drugs that combat HIV and AIDS.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size:14px;\">Read more in <a href=\"https:\/\/www.sciencedaily.com\/releases\/2015\/07\/150701093856.htm\" rel=\"nofollow\" target=\"_blank\"><em>Science Daily<\/em><\/a>.\u00a0<\/span><\/p>\n","protected":false},"author":27,"featured_media":60567,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"new_tags":[356],"series":[],"subject":[365,2444],"class_list":["post-40601","research","type-research","status-publish","has-post-thumbnail","hentry","new_tags-356","subject-365","subject-sheng-wu-hua-xue-yi-chuan-xue-yu-fen-zi-sheng-wu-xue-314"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Researchers unravel a 3-D map of capsid protein | Editage Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Researchers unravel a 3-D map of capsid protein | Editage Insights\" \/>\n<meta property=\"og:description\" content=\"Researchers at the University of Missouri have been abl [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966\" \/>\n<meta property=\"og:site_name\" content=\"Editage Insights\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Editage\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-08T05:46:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png\" \/>\n\t<meta property=\"og:image:width\" content=\"656\" \/>\n\t<meta property=\"og:image:height\" content=\"336\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Editage\" \/>\n<meta name=\"twitter:label1\" content=\"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 \u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966\\\/\",\"url\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966\",\"name\":\"Researchers unravel a 3-D map of capsid protein | Editage Insights\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966#primaryimage\"},\"image\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"datePublished\":\"2015-07-07T01:30:28+00:00\",\"dateModified\":\"2026-01-08T05:46:09+00:00\",\"breadcrumb\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966#breadcrumb\"},\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\\\/\\\/localhost\\\/editagechinanew\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966#primaryimage\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"contentUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"width\":656,\"height\":336},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/researchers-unravel-a-3d-map-of-capsid-protein-4966#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Researchers unravel a 3-D map of capsid protein\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#website\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\",\"name\":\"Editage Insights\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#organization\",\"name\":\"Editage Insights\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Editage Insights\"},\"image\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/Editage\",\"https:\\\/\\\/x.com\\\/Editage\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Researchers unravel a 3-D map of capsid protein | Editage Insights","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966","og_locale":"zh_CN","og_type":"article","og_title":"Researchers unravel a 3-D map of capsid protein | Editage Insights","og_description":"Researchers at the University of Missouri have been abl [&hellip;]","og_url":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966","og_site_name":"Editage Insights","article_publisher":"https:\/\/www.facebook.com\/Editage","article_modified_time":"2026-01-08T05:46:09+00:00","og_image":[{"width":656,"height":336,"url":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@Editage","twitter_misc":{"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4":"1 \u5206"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.editage.cn\/insights\/researchers-unravel-a-3d-map-of-capsid-protein-4966\/","url":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966","name":"Researchers unravel a 3-D map of capsid protein | Editage Insights","isPartOf":{"@id":"https:\/\/www.editage.cn\/insights\/#website"},"primaryImageOfPage":{"@id":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966#primaryimage"},"image":{"@id":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966#primaryimage"},"thumbnailUrl":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","datePublished":"2015-07-07T01:30:28+00:00","dateModified":"2026-01-08T05:46:09+00:00","breadcrumb":{"@id":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966#breadcrumb"},"inLanguage":"zh-Hans","potentialAction":[{"@type":"ReadAction","target":["http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966"]}]},{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966#primaryimage","url":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","contentUrl":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","width":656,"height":336},{"@type":"BreadcrumbList","@id":"http:\/\/localhost\/editagechinanew\/researchers-unravel-a-3d-map-of-capsid-protein-4966#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.editage.cn\/insights\/"},{"@type":"ListItem","position":2,"name":"Researchers unravel a 3-D map of capsid protein"}]},{"@type":"WebSite","@id":"https:\/\/www.editage.cn\/insights\/#website","url":"https:\/\/www.editage.cn\/insights\/","name":"Editage Insights","description":"","publisher":{"@id":"https:\/\/www.editage.cn\/insights\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.editage.cn\/insights\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-Hans"},{"@type":"Organization","@id":"https:\/\/www.editage.cn\/insights\/#organization","name":"Editage Insights","url":"https:\/\/www.editage.cn\/insights\/","logo":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Editage Insights"},"image":{"@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/Editage","https:\/\/x.com\/Editage"]}]}},"_links":{"self":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research\/40601","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research"}],"about":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/types\/research"}],"author":[{"embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/users\/27"}],"version-history":[{"count":1,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research\/40601\/revisions"}],"predecessor-version":[{"id":60235,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/research\/40601\/revisions\/60235"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/media\/60567"}],"wp:attachment":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/media?parent=40601"}],"wp:term":[{"taxonomy":"new_tags","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/new_tags?post=40601"},{"taxonomy":"series","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/series?post=40601"},{"taxonomy":"subject","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/subject?post=40601"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}