{"id":40518,"date":"2014-11-14T13:37:03","date_gmt":"2014-11-14T08:07:03","guid":{"rendered":"https:\/\/new.editage.cn\/insights\/research\/drug-resistant-cancer-responds-to-personalized-drug-combinations"},"modified":"2026-01-08T11:15:53","modified_gmt":"2026-01-08T05:45:53","slug":"drugresistant-cancer-responds-to-personalized-drug-combinations-4883","status":"publish","type":"research","link":"https:\/\/www.editage.cn\/insights\/drugresistant-cancer-responds-to-personalized-drug-combinations-4883\/","title":{"rendered":"Drug-resistant cancer responds to personalized drug combinations"},"content":{"rendered":"

Cancer researcher and physician Jeffrey Engelman<\/a> of the Massachusetts General Hospital in Boston has found a promising way of treating drug-resistant cancer by growing patients\u2019 tumor cells and testing various drug combinations on them to find a way of effective treatment. Engelman and his colleagues devised a way to culture lung cancer cells from patient samples and then test them against a battery of 76 different drugs, and they got encouraging results. According to the researcher, this cell-culture model could make personalized drug screening faster as compared to using a mouse model. However, the team reported that they got unexpected results during their study; for example, cell samples that were resistant to therapies targeting a protein called ALK were felled by different drugs that inhibited another protein called SRC. Further research is required before this treatment can be used for patients.<\/span><\/span><\/p>\n

Read more in Nature<\/a><\/em>. \u00a0 \u00a0<\/span><\/span><\/p>\n","protected":false},"author":27,"featured_media":60567,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"new_tags":[356],"series":[],"subject":[365,2444],"class_list":["post-40518","research","type-research","status-publish","has-post-thumbnail","hentry","new_tags-356","subject-365","subject-sheng-wu-hua-xue-yi-chuan-xue-yu-fen-zi-sheng-wu-xue-314"],"acf":[],"yoast_head":"\nDrug-resistant cancer responds to personalized drug combinations | Editage Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/localhost\/editagechinanew\/drugresistant-cancer-responds-to-personalized-drug-combinations-4883\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Drug-resistant cancer responds to 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