{"id":39624,"date":"2016-06-27T05:49:22","date_gmt":"2016-06-27T00:19:22","guid":{"rendered":"https:\/\/new.editage.cn\/insights\/%e7%be%8e%e5%9b%bd%e5%9b%bd%e7%ab%8b%e5%8d%ab%e7%94%9f%e7%a0%94%e7%a9%b6%e9%99%a2-nih-%e9%80%9a%e8%bf%87%e5%85%a8%e7%90%83%e9%a6%96%e4%be%8b%e5%9f%ba%e5%9b%a0%e7%bc%96%e8%be%91%e6%8a%80%e6%9c%af-cri"},"modified":"2026-01-07T16:23:50","modified_gmt":"2026-01-07T10:53:50","slug":"mei-guo-guo-li-wei-sheng-yan-jiu-yuan-nih-tong-guo-quan-qiu-shou-li-ji-yin-bian-ji-ji-shu-crispr-lin-chuang-sh-2602","status":"publish","type":"post","link":"https:\/\/www.editage.cn\/insights\/mei-guo-guo-li-wei-sheng-yan-jiu-yuan-nih-tong-guo-quan-qiu-shou-li-ji-yin-bian-ji-ji-shu-crispr-lin-chuang-sh-2602\/","title":{"rendered":"\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662 (NIH) \u901a\u8fc7\u5168\u7403\u9996\u4f8b\u57fa\u56e0\u7f16\u8f91\u6280\u672f CRISPR \u4e34\u5e8a\u8bd5\u9a8c"},"content":{"rendered":"<p>CRISPR-Cas9 \u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5728\u7f8e\u56fd\u51c6\u5907\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002\u7f8e\u56fd<a href=\"https:\/\/www.nih.gov\/\" rel=\"nofollow\" target=\"_blank\">\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662<\/a>\u00a0(National Institutes of Health, NIH) \u5df2\u7ecf\u901a\u8fc7\u8be5\u6280\u672f\u4f7f\u7528\u5728\u764c\u75c7\u6cbb\u7597\u7684\u63d0\u6848\u3002<\/p>\n<p>6 \u6708 21 \u65e5\uff0cNIH\u00a0\u8054\u90a6\u4f26\u7406\u548c\u751f\u7269\u5b89\u5168\u5c0f\u7ec4\u91cd\u7ec4 DNA \u987e\u95ee\u59d4\u5458\u4f1a (Recombinant\u00a0DNA\u00a0Advisory\u00a0Committee, RAC) \u6279\u51c6\u4e86\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u00a0Edward Stadtmauer \u56e2\u961f\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8ba1\u5212\u3002\u8be5\u4e34\u5e8a\u8bd5\u9a8c\u5c06\u7531 Facebook \u524d\u4e3b\u5e2d Sean Parker \u6240\u521b\u7acb\u7684<a href=\"https:\/\/www.parkerici.org\/\" rel=\"nofollow\" target=\"_blank\">\u5e15\u514b\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7814\u7a76\u6240<\/a> (Parker Institute for Cancer Immunotherapy) \u63d0\u4f9b\u8d44\u52a9\u3002<\/p>\n<p>\u4e3a\u671f\u4e24\u5e74\u7684\u8bd5\u9a8c\u9879\u76ee\u9884\u8ba1\u5c06\u6709 18 \u4f4d\u6709\u9aa8\u9ad3\u7624\u3001\u8089\u7624\u6216\u9ed1\u8272\u7d20\u7624\u7684\u75c5\u60a3\u53c2\u4e0e\uff0c\u4e14\u5bf9\u6d3e\u514b\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7814\u7a76\u6240\u73b0\u6709\u7684\u6cbb\u7597\u65b9\u5f0f\u6ca1\u6709\u53cd\u5e94\u3002\u7814\u7a76\u56e2\u961f\u7684\u4e3b\u8981\u76ee\u7684\u662f\u7f16\u8f91\u75c5\u60a3\u8eab\u4f53\u5185\u7684\u514d\u75ab\u7ec6\u80de T \u7ec6\u80de\uff0c\u8ba9 T \u7ec6\u80de\u53ef\u4ee5\u627e\u5230\u5e76\u653b\u51fb\u764c\u7ec6\u80de\u3002<\/p>\n<p>\u5c3d\u7ba1 RAC \u5df2\u7ecf\u6838\u51c6\u8fd9\u9879\u8ba1\u5212\uff0cStadtmauer \u8fd8\u9700\u8981\u53d6\u5f97\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u7ba1\u7406\u5c40\uff08Food and Drug Administration\uff0cFDA\uff09\u7684\u8bb8\u53ef\uff0c\u540c\u65f6\u4e5f\u5fc5\u987b\u53d6\u5f97\u7814\u7a76\u5c0f\u7ec4\u6210\u5458\u6240\u5728\u7684\u5ba1\u67e5\u59d4\u5458\u4f1a\u6838\u51c6\u3002\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u514d\u75ab\u5b66\u5bb6\uff0c\u540c\u65f6\u4e5f\u662f\u6b64\u9879\u76ee\u6848\u7684\u79d1\u5b66\u6307\u5bfc\u987e\u95ee <a href=\"https:\/\/www.nature.com\/news\/first-crispr-clinical-trial-gets-green-light-from-us-panel-1.20137\" rel=\"nofollow\" target=\"_blank\">Carl June \u8868\u793a<\/a>\u8fd9\u4e2a\u8bd5\u9a8c\u53ef\u671b\u5728\u4eca\u5e74\u5e95\u6b63\u5f0f\u542f\u52a8\uff0c\u4f7f\u7528 CRISPR \u7684\u4e3b\u8981\u6311\u6218\u4f1a\u662f\u907f\u514d\u57fa\u56e0\u7a81\u53d8\u610f\u5916\u3002<\/p>\n<p>\u8bb8\u591a\u516c\u53f8\u90fd\u5728\u4e89\u53d6\u8fd9\u9879\u6280\u672f\u7684\u5546\u4e1a\u5316\u673a\u4f1a\uff0c\u4e5f\u6709\u597d\u51e0\u4e2a\u5355\u4f4d\u548c\u7814\u7a76\u56e2\u4f53\u8868\u793a\u5e0c\u671b\u4f7f\u7528\u8fd9\u9879\u6280\u672f\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e0a\u3002\u867d\u7136\u8fd9\u6b21\u8bd5\u9a8c\u7684\u6838\u51c6\u9f13\u821e\u4e86\u9057\u4f20\u5b66\u5bb6\uff0c\u4f46\u8bd5\u9a8c\u7ed3\u679c\u662f\u5426\u80fd\u8ba9\u6211\u4eec\u66f4\u4e86\u89e3 CRIPR\uff0c\u8ba9\u66f4\u591a\u4f7f\u7528\u8fd9\u9879\u6280\u672f\u7684\u8bd5\u9a8c\u53d6\u5f97\u6838\u51c6\uff0c\u4ecd\u6709\u5f85\u8003\u9a8c\u3002<\/p>\n<p style=\"text-align: justify;\">\u00a0<\/p>\n<p style=\"text-align: justify;\"><strong>\u53c2\u8003\u8d44\u6599<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/news\/first-crispr-clinical-trial-gets-green-light-from-us-panel-1.20137\" rel=\"nofollow\">First CRISPR clinical trial gets green light from US panel<\/a><\/li>\n<li style=\"text-align: justify;\"><a href=\"https:\/\/www.sciencemag.org\/news\/2016\/06\/human-crispr-trial-proposed\" rel=\"nofollow\">First proposed human test of CRISPR passes initial safety review<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>CRISPR-Cas9 \u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5728\u7f8e\u56fd\u51c6\u5907\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u00a0(National Ins 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