{"id":39520,"date":"2016-01-18T10:07:20","date_gmt":"2016-01-18T04:37:20","guid":{"rendered":"https:\/\/new.editage.cn\/insights\/crispr-%e4%b8%93%e5%88%a9%e5%a4%a7%e6%88%98%ef%bc%9adoudna-%e5%92%8c-charpentier-%e4%b8%8e%e5%bc%a0%e9%94%8b%e9%97%b4%e7%9a%84%e5%8f%b8%e6%b3%95%e7%ba%a0%e7%ba%b7"},"modified":"2026-01-07T16:22:44","modified_gmt":"2026-01-07T10:52:44","slug":"crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494","status":"publish","type":"post","link":"https:\/\/www.editage.cn\/insights\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\/","title":{"rendered":"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7"},"content":{"rendered":"<p>CRISPR-Cas9 \u57fa\u56e0\u7ec4\u7f16\u8f91\u6280\u672f\u7684\u4e13\u5229\u5927\u6218\u5c1a\u672a\u505c\u6b47\u3002CRISPR \u7684\u5168\u79f0\u4e3a clustered regularly-interspaced short palindromic repeats \u7684\u7b80\u79f0\uff0c\u6709\u53ef\u80fd\u8ba9\u4eba\u7c7b\u514d\u4e8e\u81f4\u547d\u75be\u75c5\u5e76\u5728\u5b9e\u9a8c\u5ba4\u57f9\u517b\u5668\u5b98\uff0c\u53f7\u79f0\u662f <a href=\"https:\/\/www.sciencemag.org\/topic\/2015-breakthrough-year\" rel=\"nofollow\" target=\"_blank\">2014 \u5e74\u6700\u5927\u7684\u7a81\u7834\u4e4b\u4e00<\/a>\u3002<\/p>\n<p>\u4f2f\u514b\u5229\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u7684 Jennifer Doudna \u548c\u5fb7\u56fd\u4ea5\u59c6\u970d\u5179\u533b\u5b66\u7814\u7a76\u4e2d\u5fc3\u7684 Emmanuelle Charpentier \u6559\u6388\u641c\u7533\u8bf7\u4e86\u5728\u54fa\u4e73\u52a8\u7269\u7ec6\u80de\u4e0a\u4f7f\u7528 CRISPR \u6280\u672f\u7684\u4e13\u5229\uff0c\u7136\u800c\u7f8e\u56fd\u4e13\u5229\u5546\u6807\u5c40\uff08U.S. Patent and Trademark Office\uff0cUSPTO\uff09<a href=\"https:\/\/acts.uspto.gov\/ifiling\/PDFfromDocumentum?No=106048&amp;docTy=NOTICE+TO+DECLARE+INTERFERENCE&amp;action=getContentByDocType\" rel=\"nofollow\" target=\"_blank\">\u5df2\u6388\u6743\u8fd9\u4e9b\u4e13\u5229\u7ed9\u5f20\u950b\u5c0f\u7ec4<\/a>\uff0c\u5f20\u950b\u662f\u7f8e\u56fd\u54c8\u4f5b-\u9ebb\u7701\u7406\u5de5\u7684\u535a\u5fb7\u7814\u7a76\u6240\uff08Broad\u00a0Institute\u00a0of\u00a0MIT\u00a0and\u00a0Harvard\uff09\u7684\u79d1\u5b66\u5bb6\uff0c\u4ed6\u62e5\u6709 12 \u9879\u4f7f\u7528 CRISPR \u7684\u4e13\u5229\u3002<\/p>\n<p>\u8fd9\u573a\u6cd5\u5f8b\u7ea0\u7eb7\u4e3b\u8981\u56e0 Doudna \u548c Charpentier \u800c\u8d77\uff0c\u6240\u5c5e\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u7684\u4e24\u4eba\u5728 2013 \u5e74 3 \u6708\u63d0\u51fa\u4e13\u5229\u7533\u8bf7\uff0c\u800c\u5f20\u950b\u5219\u662f\u5728 2013 \u5e74 10 \u6708\u9012\u4ea4\u7684\u7533\u8bf7\uff0c\u4f46\u7531\u4e8e\u5f20\u950b\u6240\u5c5e\u5355\u4f4d\u7533\u8bf7\u4e86\u7279\u6b8a\u5feb\u901f\u901a\u9053\uff0c\u4ed6\u5728 2014 \u5e74 4 \u6708\u5148\u4e8e Doudna \u548c Charpentier \u53d6\u5f97\u4e13\u5229\u6743\u3002\u56e0\u6b64\u52a0\u5229\u798f\u5c3c\u4e9a\u5927\u5b66\u8981\u6c42 USPTO \u91cd\u65b0\u5ba1\u67e5\u4e13\u5229\u8d44\u683c\uff0c\u5e76\u63d0\u51fa\u5e72\u6270\u8bc9\u8bbc\uff0c\u5e0c\u671b\u771f\u6b63\u7684\u6280\u672f\u53d1\u660e\u8005\u80fd\u53d6\u5f97\u4e13\u5229\u3002<\/p>\n<p>\u65e9\u5148 USPTO \u662f\u5c06\u4e13\u5229\u6388\u4e88\u9996\u6b21\u53d1\u660e\u4eba\u5458\uff0c\u4f46\u8fd9\u4e2a\u89c4\u5b9a\u5728 2013 \u5e74\u4fee\u6b63\uff0c\u73b0\u5728\u7684\u4e13\u5229\u662f\u7531\u5148\u7533\u8bf7\u8005\u5f97\u5230\u3002Doudna \u548c Charpentier \u5728\u8fd9\u6761\u89c4\u5b9a\u4fee\u6539\u524d\u5c31\u9012\u4ea4\u7533\u8bf7\uff0c\u5148\u524d\u7684\u89c4\u5b9a\u6709\u53ef\u80fd\u4f7f\u7528\u8fd9\u6b21\u6848\u4f8b\u3002\u5355\u4f4d\u95f4\u7684\u4e13\u5229\u7ea0\u7eb7\u76f8\u5f53\u5e38\u89c1\uff0c\u4f46\u4e0d\u5982\u8fd9\u6b21\u6765\u7684\u6fc0\u70c8\u3002\u8fbe\u52d2\u59c6\u675c\u514b\u5927\u5b66\u6cd5\u5f8b\u5b66\u8005 Arti Rai \u5c31\u8bf4\uff1a\u300c<a href=\"https:\/\/www.nature.com\/news\/bitter-fight-over-crispr-patent-heats-up-1.17961\" rel=\"nofollow\" target=\"_blank\">\u8fd9\u770b\u8d77\u6765\u662f\u6211\u76ee\u524d\u9047\u8fc7\u6700\u6fc0\u70c8\u7684\u7ea0\u7eb7\u3002<\/a>\u300d<\/p>\n<p>\u00a0\u6709\u5f88\u591a\u8981\u7b49\u6cd5\u5f8b\u8bc9\u8bbc\u7ed3\u679c\u51fa\u6765\u540e\u624d\u80fd\u518d\u63a8\u8fdb\uff0c\u5f97\u5230\u4e13\u5229\u6743\u7684\u4eba\u90fd\u5c06\u83b7\u5f97\u91d1\u94b1\u5229\u76ca\uff1a\u4efb\u4f55\u60f3\u8981\u5c06\u8fd9\u9879\u6280\u672f\u7528\u4e8e\u5546\u4e1a\u7528\u9014\u7684\u516c\u53f8\u90fd\u9700\u8981\u53d6\u5f97\u4e13\u5229\u6743\u6240\u6709\u8005\u7684\u6388\u6743\u3002\u76ee\u524d\u5df2\u7ecf\u6709\u8bb8\u591a\u516c\u53f8\u60f3\u8981\u4f7f\u7528 CRISPR \u6280\u672f\uff0c\u4e5f\u4ece\u6295\u8d44\u8005\u52df\u5f97\u5ba2\u89c2\u7684\u8d44\u91d1\uff0c\u6295\u8d44\u8005\u8ba4\u4e3a\u8fd9\u9879\u6280\u672f\u53ef\u5e94\u7528\u5230\u5546\u4e1a\u4e0a\u5f00\u53d1\u65b0\u7684\u6cbb\u7597\u65b9\u5f0f\uff0c\u4f8b\u5982\u4e00\u95f4\u5251\u6865\u65b0\u521b\u516c\u53f8\u00a0Editas Medicine \u5c31\u5bf9 CRISPR \u6280\u672f\u6709\u5174\u8da3\uff0c\u4ed6\u4eec\u6700\u8fd1\u5ba3\u5e03<a href=\"https:\/\/www.washingtonpost.com\/news\/wonk\/wp\/2016\/01\/13\/control-of-crispr-biotechs-most-promising-breakthrough-is-up-for-grabs\/\" rel=\"nofollow\" target=\"_blank\">\u4e00\u4ebf\u7f8e\u5143\u7684\u521d\u6b21\u516c\u5f00\u52df\u80a1<\/a>\u3002<\/p>\n<p>USPTO \u5c06 Doudna \u4e00\u65b9\u5b9a\u4e49\u4e3a\u201csenior party\u201d\uff0c\u800c\u5f20\u950b\u4e00\u65b9\u662f\u201cjunior party\u201d\uff0c\u8868\u793a Doudna \u4f3c\u4e4e\u662f CRISPR \u7684\u6700\u5148\u53d1\u660e\u4eba\u3002\u4f46\u4e3a\u4e86\u505a\u51fa\u516c\u5e73\u516c\u6b63\u7684\u51b3\u5b9a\uff0c\u53cc\u65b9\u5fc5\u987b\u63d0\u4f9b\u5145\u8db3\u7684\u8bc1\u636e\u6b63\u5e73\u81ea\u5df1\u662f\u8fd9\u9879\u6280\u672f\u7684\u53d1\u660e\u4eba\u3002USPTO \u6307\u51fa\u5df2\u6709\u4e09\u4f4d\u4e13\u5bb6\u7ec4\u6210\u4e13\u5229\u590d\u5ba1\u5c0f\u7ec4\uff0c\u4ed6\u4eec\u4f1a\u51b3\u5b9a\u54ea\u4e00\u4e2a\u5c0f\u7ec4\u662f\u4e13\u5229\u6240\u6709\u4eba\u3002<\/p>\n<p>\u597d\u6d88\u606f\u662f\uff0c\u8fd9\u4e24\u4e2a\u5355\u4f4d\u90fd\u4f1a\u514d\u8d39\u5f00\u653e\u8fd9\u9879\u6280\u672f\u7528\u6765\u8fdb\u884c\u57fa\u7840\u7814\u7a76\uff0c\u65e5\u540e\u4e5f\u4f1a\u4e00\u76f4\u5982\u6b64\u3002\u7a76\u7adf\u8c01\u4f1a\u62ff\u5230\u4e13\u5229\u6743\uff0c\u4e14\u62ed\u76ee\u4ee5\u5f85\u3002<\/p>\n<p>\u00a0<\/p>\n<p><strong>\u53c2\u8003\u8d44\u6599\uff1a<\/strong><\/p>\n<p><a href=\"https:\/\/www.nature.com\/news\/bitter-fight-over-crispr-patent-heats-up-1.17961\" rel=\"nofollow\"><em>Bitter fight over CRISPR patent heats up<\/em><\/a><em>\u00a0(accessed January 15)<\/em><\/p>\n<p><a href=\"https:\/\/www.washingtonpost.com\/news\/wonk\/wp\/2016\/01\/13\/control-of-crispr-biotechs-most-promising-breakthrough-is-up-for-grabs\/\" rel=\"nofollow\"><em>Control of CRISPR, biotech\u2019s most promising breakthrough, is in dispute<\/em><\/a><em>\u00a0(accessed January 15)<\/em><\/p>\n<p><a href=\"https:\/\/www.technologyreview.com\/view\/545411\/crispr-dispute-to-be-decided-by-patent-office\/\" rel=\"nofollow\"><em>CRISPR Dispute to Be Decided by Patent Office<\/em><\/a><em>\u00a0(accessed January 15)<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CRISPR-Cas9 \u57fa\u56e0\u7ec4\u7f16\u8f91\u6280\u672f\u7684\u4e13\u5229\u5927\u6218\u5c1a\u672a\u505c\u6b47\u3002CRISPR \u7684\u5168\u79f0\u4e3a clustered regu [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":60567,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[528,55],"tags":[13],"new_categories":[],"new_tags":[],"series":[],"class_list":["post-39520","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ke-yan-fa-biao-xin-xiao-xi-155","category-hang-ye-xin-wen-31","tag-ke-yan-fa-biao-xin-xiao-xi-155"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7 | Editage Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7 | Editage Insights\" \/>\n<meta property=\"og:description\" content=\"CRISPR-Cas9 \u57fa\u56e0\u7ec4\u7f16\u8f91\u6280\u672f\u7684\u4e13\u5229\u5927\u6218\u5c1a\u672a\u505c\u6b47\u3002CRISPR \u7684\u5168\u79f0\u4e3a clustered regu [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\" \/>\n<meta property=\"og:site_name\" content=\"Editage Insights\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Editage\" \/>\n<meta property=\"article:published_time\" content=\"2016-01-18T04:37:20+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-07T10:52:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png\" \/>\n\t<meta property=\"og:image:width\" content=\"656\" \/>\n\t<meta property=\"og:image:height\" content=\"336\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Sneha Kulkarni\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Editage\" \/>\n<meta name=\"twitter:site\" content=\"@Editage\" \/>\n<meta name=\"twitter:label1\" content=\"\u4f5c\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sneha Kulkarni\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\\\/\"},\"author\":{\"name\":\"Sneha Kulkarni\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/person\\\/b8494f2ddcaba7259514729f30533ec6\"},\"headline\":\"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7\",\"datePublished\":\"2016-01-18T04:37:20+00:00\",\"dateModified\":\"2026-01-07T10:52:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\\\/\"},\"wordCount\":85,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#organization\"},\"image\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"keywords\":[\"\u79d1\u7814\u53d1\u8868\u65b0\u6d88\u606f\"],\"articleSection\":[\"\u79d1\u7814\u53d1\u8868\u65b0\u6d88\u606f\",\"\u884c\u4e1a\u65b0\u95fb\"],\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\\\/\",\"url\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\",\"name\":\"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7 | Editage Insights\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage\"},\"image\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"datePublished\":\"2016-01-18T04:37:20+00:00\",\"dateModified\":\"2026-01-07T10:52:44+00:00\",\"breadcrumb\":{\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#breadcrumb\"},\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"contentUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/editage-insights-generic-banner_298.png\",\"width\":656,\"height\":336},{\"@type\":\"BreadcrumbList\",\"@id\":\"http:\\\/\\\/localhost\\\/editagechinanew\\\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#website\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\",\"name\":\"Editage Insights\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#organization\",\"name\":\"Editage Insights\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Editage Insights\"},\"image\":{\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/Editage\",\"https:\\\/\\\/x.com\\\/Editage\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/#\\\/schema\\\/person\\\/b8494f2ddcaba7259514729f30533ec6\",\"name\":\"Sneha Kulkarni\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\\\/\\\/www.editage.cn\\\/insights\",\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\",\"contentUrl\":\"https:\\\/\\\/www.editage.cn\\\/insights\",\"caption\":\"Sneha Kulkarni\"},\"url\":\"https:\\\/\\\/www.editage.cn\\\/insights\\\/sneha-kulkarni\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7 | Editage Insights","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494","og_locale":"zh_CN","og_type":"article","og_title":"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7 | Editage Insights","og_description":"CRISPR-Cas9 \u57fa\u56e0\u7ec4\u7f16\u8f91\u6280\u672f\u7684\u4e13\u5229\u5927\u6218\u5c1a\u672a\u505c\u6b47\u3002CRISPR \u7684\u5168\u79f0\u4e3a clustered regu [&hellip;]","og_url":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494","og_site_name":"Editage Insights","article_publisher":"https:\/\/www.facebook.com\/Editage","article_published_time":"2016-01-18T04:37:20+00:00","article_modified_time":"2026-01-07T10:52:44+00:00","og_image":[{"width":656,"height":336,"url":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","type":"image\/png"}],"author":"Sneha Kulkarni","twitter_card":"summary_large_image","twitter_creator":"@Editage","twitter_site":"@Editage","twitter_misc":{"\u4f5c\u8005":"Sneha Kulkarni"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#article","isPartOf":{"@id":"https:\/\/www.editage.cn\/insights\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\/"},"author":{"name":"Sneha Kulkarni","@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/person\/b8494f2ddcaba7259514729f30533ec6"},"headline":"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7","datePublished":"2016-01-18T04:37:20+00:00","dateModified":"2026-01-07T10:52:44+00:00","mainEntityOfPage":{"@id":"https:\/\/www.editage.cn\/insights\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\/"},"wordCount":85,"commentCount":0,"publisher":{"@id":"https:\/\/www.editage.cn\/insights\/#organization"},"image":{"@id":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage"},"thumbnailUrl":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","keywords":["\u79d1\u7814\u53d1\u8868\u65b0\u6d88\u606f"],"articleSection":["\u79d1\u7814\u53d1\u8868\u65b0\u6d88\u606f","\u884c\u4e1a\u65b0\u95fb"],"inLanguage":"zh-Hans","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.editage.cn\/insights\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494\/","url":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494","name":"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7 | Editage Insights","isPartOf":{"@id":"https:\/\/www.editage.cn\/insights\/#website"},"primaryImageOfPage":{"@id":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage"},"image":{"@id":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage"},"thumbnailUrl":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","datePublished":"2016-01-18T04:37:20+00:00","dateModified":"2026-01-07T10:52:44+00:00","breadcrumb":{"@id":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#breadcrumb"},"inLanguage":"zh-Hans","potentialAction":[{"@type":"ReadAction","target":["http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494"]}]},{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#primaryimage","url":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","contentUrl":"https:\/\/www.editage.cn\/insights\/wp-content\/uploads\/2026\/02\/editage-insights-generic-banner_298.png","width":656,"height":336},{"@type":"BreadcrumbList","@id":"http:\/\/localhost\/editagechinanew\/crispr-zhuan-li-da-zhan-doudna-he-charpentier-yu-zhang-feng-jian-de-si-fa-jiu-fen-2494#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.editage.cn\/insights\/"},{"@type":"ListItem","position":2,"name":"CRISPR \u4e13\u5229\u5927\u6218\uff1aDoudna \u548c Charpentier \u4e0e\u5f20\u950b\u95f4\u7684\u53f8\u6cd5\u7ea0\u7eb7"}]},{"@type":"WebSite","@id":"https:\/\/www.editage.cn\/insights\/#website","url":"https:\/\/www.editage.cn\/insights\/","name":"Editage Insights","description":"","publisher":{"@id":"https:\/\/www.editage.cn\/insights\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.editage.cn\/insights\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"zh-Hans"},{"@type":"Organization","@id":"https:\/\/www.editage.cn\/insights\/#organization","name":"Editage Insights","url":"https:\/\/www.editage.cn\/insights\/","logo":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Editage Insights"},"image":{"@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/Editage","https:\/\/x.com\/Editage"]},{"@type":"Person","@id":"https:\/\/www.editage.cn\/insights\/#\/schema\/person\/b8494f2ddcaba7259514729f30533ec6","name":"Sneha Kulkarni","image":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/www.editage.cn\/insights","url":"https:\/\/www.editage.cn\/insights","contentUrl":"https:\/\/www.editage.cn\/insights","caption":"Sneha Kulkarni"},"url":"https:\/\/www.editage.cn\/insights\/sneha-kulkarni"}]}},"_links":{"self":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/posts\/39520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/comments?post=39520"}],"version-history":[{"count":1,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/posts\/39520\/revisions"}],"predecessor-version":[{"id":58302,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/posts\/39520\/revisions\/58302"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/media\/60567"}],"wp:attachment":[{"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/media?parent=39520"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/categories?post=39520"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/tags?post=39520"},{"taxonomy":"new_categories","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/new_categories?post=39520"},{"taxonomy":"new_tags","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/new_tags?post=39520"},{"taxonomy":"series","embeddable":true,"href":"https:\/\/www.editage.cn\/insights\/wp-json\/wp\/v2\/series?post=39520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}