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A new human interactome map created using the yeast two-hybrid system

意得辑专家视点 | 2014年11月27日 | 1,806 浏览次数
A new human interactome map created using the yeast two-hybrid system

Although researchers have succeeded in sequencing human genome, to expand the knowledge of functional elements within the genome, a thorough study of how human proteins operate and interact is essential. Researchers at the Dana-Farber Cancer Institute’s Center for Cancer Systems Biology have made detailed study of genome functioning possible by creating a new human interactome map. The map is based on a systematic screen of 13,000 human proteins that revealed 14,000 pairwise interactions. The researchers have documented about 5 percent to 10 percent of all the protein-protein interactions that exist using the yeast two-hybrid system. This comprehensive study can prove to be valuable in the study of chronic diseases such as cancer.

Read more in The Scientist.  

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